Quercetin, kaempferol, and β-sitosterol were the top three promising active ingredients, which could act on multiple targets like PTGS2, HSP90AA1, and PTGS1 and regulate multiple biological pathways like IL-17 signaling pathway, TNF signaling pathway, and PI3K-Akt signaling pathway to relieve HF. This evidence concerns the gene PTGS2 and hydrops fetalis.