MAPK3 and atopic eczema: The investigators reported that in skin inflammation lesions, leaf extract inhibited macrophage-derived chemokine (MDC/CCL22) production via the downregulation of (STAT) 1 and extracellular signal-regulated kinase 1/2 (ERK1/2) pathways and, hence, improved several symptoms (ear edema and lymph node size) change in blood parameter (serum IgE) and histological changes in mice with allergic dermatitis.