MRC1 and neoplasm: We found that IFN-γ/St.∆ppGpp increased the numbers of both CD86+ (Figures 4A,B and CD206+ (Figures 4C,D) cells in tumor sections when compared with St.∆ppGpp-alone, suggesting that although IFN-γ/St.∆ppGpp did not affect macrophage polarization, it increased the number of M1-type TAMs.