PLOD1 and hypothyroidism: A study (61) investigated the effects of hypothyroidism on hormones in mature female rats and reported that there was a significant increase in progesterone levels in the PTU group, the LH level was significantly lower in hypothyroid rats, the E2 and FSH levels in the thyroidectomy group tended to decrease compared with the control group, but there was no difference in terms of the FSH level between the PTU group and the control group.