Besides, critical chemokine ligand family members (including CXCL1, CXCL2, CXCL5, CXCL8, and CXCL11), which involved in tumor growth regulation and metastasis and mediated the enrichment of CD8+ T cells into the TME, were upregulated in the high AI score subtype. The gene discussed is CXCL8; the disease is neoplasm.