In contrast, ALB, TF, PA, and Hb were effectively elevated in patients with COPD combined with RF under the three nutritional support regimens of enteral, parenteral, and EPNS, with the most remarkable tips in group C patients using EPNS, which is also consistent with the results of previous studies [24] and can confirm the value of EPNS in COPD. This evidence concerns the gene ALB and chronic obstructive pulmonary disease.