As proposed by Wu et al. [21], a TME risk model constructed with the tumor immune infiltration-related genes SERPINE1, CX3CR1, CD200R1, GBP1, IRF1, STAP1, LOX, and OR7E47P based on public databases can be used to predict the prognostic survival of LC patients. This evidence concerns the gene STAP1 and laryngotracheoesophageal cleft.