IRF1 and laryngotracheoesophageal cleft: As proposed by Wu et al. [21], a TME risk model constructed with the tumor immune infiltration-related genes SERPINE1, CX3CR1, CD200R1, GBP1, IRF1, STAP1, LOX, and OR7E47P based on public databases can be used to predict the prognostic survival of LC patients.