Second, keyword analysis suggested that, in addition to these well-established asthma diagnostic techniques based on symptoms, exhaled nitric oxide, lung function, and detection of IgE immunoreactivity against specific allergens, potential biomarkers from multi-omics remain to be discovered to either assist the precise diagnosis/prediction of asthma or facilitate personalized treatment of the disease at the molecular level (74). This evidence concerns the gene IGHE and asthma.