AMoL may be also rarely associated with Core Binding Factor (CBF) mutations involving chromosome 16 [inv (16) (p13.1q22) and t (16; 16) (p13.1; q22)/CBFB-MYH11], and t (8; 21) (q22; q22.1); RUNX1-RUNX1T1, both included in the category AML with recurrent genetic abnormalities according to WHO classification (1, 3, 91, 92). This evidence concerns the gene CEBPZ and acute myeloid leukemia.