For instance, we just disclosed the molecular mechanism of the NORAD/miR-28-3p/E2F2 ceRNA interaction, but the effect of other downstream genes of NORAD or miR-28-3p is still elusive, and the role of the NORAD/miR-28-3p/E2F2 in LC cell apoptosis remains unknown. Here, E2F2 is linked to laryngotracheoesophageal cleft.