In this research, we detected the expression of lncRNA MIAT and miR-361-3p in prostate cancer tissues and adjacent nontumor tissues, and found that lncRNA MIAT was upregulated in the prostate cancer tissues compared with adjacent nontumor tissues, which was opposite to the expression level of miR-361-3p in the prostate cancer tissues. This evidence concerns the gene MIAT and Familial prostate cancer.