According to the results of recent studies, many favorable prognostic factors have been suggested, such as primary cancer (lower T and N stage, no lympho-vascular or serosal invasion), burden of hepatic disease (≤ 3 metastases, unilobar involvement, greatest lesion < 5 cm, and negative resection margins), and lower CEA and CA19.9 levels (9, 20, 21). Here, CEACAM5 is linked to cancer.