TGFB1 and breast cancer: For example, the development of non-small lung tumors can been significantly inhibited by the omega-3 polyunsaturated fatty acid DHA (37), and TGF-β-induced epithelial-to-mesenchymal transition (EMT) in human breast cancer cells is suppress by DHA (38), etc. In the present study, omega-3 dramatically decreased KGN cells development and increased cellular apoptosis as a positive effector.