Meanwhile, cytotoxicity assays showed decreased cytotoxicity in MM‐derived ZNF683+ NK cells when compared with healthy volunteers‐derived NK cells, while an increase of NK cell cytotoxicity against target cells was observed in ZNF683‐KD NK cells from MM patients (Figure S9B), further confirming the adverse effect of ZNF683 overexpression on NK cell phenotypes and functions in MM. The gene discussed is ZNF683; the disease is Miyoshi myopathy.