INS and Hypercholesterolemia: There were no differences between patients with MACE and without MACE in terms of age (p = 0.44), sex (p = 0.13), BMI (p = 0.22), diabetes duration (p = 0.92), history of high blood pressure (p = 0.48) and hypercholesterolemia (p = 0.40), history of CAD (p = 0.66) and CVD (p = 0.75), antidiabetic oral medications (p = 0.74) and insulin (p = 0.57), total cholesterol levels (p = 0.67), LDL-C levels (p = 0.836), ABI (p = 0.75), Rutherford category (II-4 p = 0.40, III-5 p = 0.40), glycated hemoglobin levels (p = 0.30) and renal function (p = 0.67).