The correlations between CD34 and CD105 in NF and IMT suggest a high neovascularization, probably related to the high proangiogenic activity of myofibroblasts, while the correlation between MCM2 and CD34 in IMT, and between MCM2 and CD105 in MFS, indicate the myofibroblasts pose high activity to proliferate and induce angiogenesis in these lesions. The gene discussed is MCM2; the disease is Marfan syndrome.