ENG and Marfan syndrome: A statistically significant correlation between MCM2 and CD105 immunostaining was identified in the MFS cases (p<0.0001), confirming that an increased cellular proliferation would increase vessel formation and vice versa, as observed in many other malignancies (32), and this could possibly be related to TGF β expression, which in turn would lead to myofibroblastic differentiation and interaction with Endoglin accessory protein (CD105) to trigger angiogenesis.