TNFRSF1A and cancer: Tumour Necrosis Factor-related Apoptosis-inducing Ligand Receptor 1 (TRAILR1) and Tumour Necrosis Factor Receptor 1 A (TNF-R1A/TNF-R1/TNFRSF1A) have been associated with both chronic inflammatory diseases and cancer susceptibility, thus these death receptors are thought to play an important role in immune system homeostasis.