We analyzed the correlations between the status of top 30 mutated genes and the clinicopathological characteristics, such as age, gender, Hp or HBV infection, LDH level, Eastern Cooperative Oncology Group (ECOG) score, B symptoms, International Prognostic Index (IPI), tumor stage, etc. The result was displayed in Fig. 4, and the correlations with statistical significance were summarized in Additional file 4: Table S4. The gene discussed is HP; the disease is neoplasm.