To compare the expression of MCM2 at the protein level, immunohistochemistry was performed using the HCC and paraneoplastic tissue sections of patients from the First Affiliated Hospital of Guangxi Medical University (Fig. 1e), Yulin First People’s Hospital (Fig. S1a), and Liuzhou People’s Hospital (Fig. S1b). This evidence concerns the gene MCM2 and hepatocellular carcinoma.