Only 5 genes were consistently implicated in both MDD and schizophrenia: in both the Blueprint and Soskic datasets, COA8/APOPT1 (a proapoptotic mitochondrial protein) and MAD1L1 (a checkpoint protein); and in the Soskic dataset only, FURIN (a protease), SNORD18 (a non-coding RNA), and RP11-73M18.2 (a kinesin light chain). Here, COA8 is linked to major depressive disorder.