According to the ATC classification, cardiovascular medicines (32.5%) (e.g. hydrochlorothiazide, furosemide, amlodipine, digoxin, enalapril, warfarin, propranolol, atorvastatin, and aspirin), the drugs of the alimentary tract and metabolism (22.4%) (e.g. metformin, Insulin, glibenclamide, propylthiouracil (PTU), vitamin B12, folic acid), and anti-infective medicines for systemic use (18.8%) (e.g. Co-trimoxazole, TB/HIV medications, amoxicillin-clavulanic acid, ceftriaxone) accounted the highest proportions of UMDs (Supplementary file 1). This evidence concerns the gene INS and tuberculosis.