Among these hub genes, 13 genes, including NCF2, FGR, ITGAL, CXCL10, LILRB2, FCGR2B, PECAM1, CD163, ITGAM, SIGLEC1, ITGAX, ITGB2 and S100A8, were significantly associated with inferior OS of AML patients (Supplementary Fig. S4). This evidence concerns the gene NCF2 and acute myeloid leukemia.