Specifically, in those areas of normal thyroid follicles and microfollicles, follicular epithelium was fairly stained for Tg, although with less intensity than the colloid; however, in HCFNs and trabecular adenomas, where the colloid was clearly diminished or absent, an apparent decrease of the cytoplasmic staining was observed (Fig. 2). This evidence concerns the gene TG and adenoma.