In addition, our RNA-Seq and qRT-PCR analyses showed that, while the expressions of IL-36RN encoding for the IL-36Ra were found to be increased in both H37Rv- and MKR-infected macrophages upon Mtb entry into host cells at 4 hr post-infection, only the expression of IL-36G was found to be up-regulated in macrophages infected with H37Rv, but not in the MKR-infected cells (Figure 7). The gene discussed is IL36RN; the disease is infection.