However, the results showed the enrichment of ontology clusters, which included the cellular response to lipid, regulation of cell morphogenesis, leukocyte migration, carbohydrate metabolic process, small GTPase mediated signal transduction, regulation of autophagy, secretion by cells, interferon-gamma production, and IL-18 signalling pathway to be uniquely upregulated in the MKR-infected macrophages at 4 hr versus that of 0 hr post-infection, but not in cells infected with H37Rv. Here, IL18 is linked to infection.