ESR1 and triple-negative breast carcinoma: Triple-negative breast cancer is a kind of breast cancer with negative expression of the estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2), and it has the characteristics of poor prognosis, strong invasion and metastasis abilities, and high mortality, so it has become the focus of research in recent years [2, 3].