To characterise macrophage plasticity and their expression of targetable chemokine receptors, we analysed F4/80+CD11b+CD11c- infiltrating macrophages (IM) and F4/80+CD11b-CD11c+ resident alveolar macrophages (AM) in a mouse model of melanoma metastasis to the lung [38–40]. The gene discussed is ITGAM; the disease is melanoma.