CD8A and neoplasm: Furthermore, coculture with Th1 OT-II cells significantly boosted the in vitro cytotoxicity of TCR Transgenic OT-I, 2 C Kb SIY, and PMEL Db gp10025-33 specific CD8+ T cells against B16-OVA (Fig. 4e and Supplementary Fig. 5h), B16-SIY (Supplementary Fig. 5i), and B16-F10 tumor cells (Supplementary Fig. 5j), respectively.