SERPINE1 and cancer: In contrast, the expression of various other chemokines and growth factors previously implicated in cancer biology were not altered neither at the mRNA level (PDGFA, PDGFB, PDGFC, IGF2, IGF1R, EGF, and EGFR; (Supplementary Fig. 11A–C) nor at the secretome level, except TGFß1 (Fig. S11D) at mRNA level and Serpin E1 and CCL2 at the secretome level (Supplementary Fig. 8C); under fibrocyte and A549 cell co-culture conditions.