We therefore evaluated the effectiveness of the PI3K inhibitor, GDC-0941/Pictilisib [46] in vivo, determining its effect on the growth of three transplanted WT Eμ-Myc, Eμ-Myc/cRel−/− and Eμ-Myc/RelAT505A tumours. The gene discussed is REL; the disease is neoplasm.