TOPBP1 and lymphoma: This experiment, originally performed before our RNA Seq and proteomic analysis of reimplanted Eμ-Myc lymphomas was completed, revealed lower levels of Claspin mRNA and protein expression in primary RelA T505A Eμ-Myc lymphomas, while ATR, CHK1, ATRIP, RAD17 and TOPBP1 were unaffected (Figure 8, Supplementary Figures S6 and S7).