PGP and cancer: EV surface molecules also confer multi‐drug resistance by expressing membrane multi‐drug efflux transporters, such as P‐glycoprotein (ABCB1/MDR1/P‐gp) (Bebawy et al., 2009; Jaiswal et al., 2012) and multidrug resistance‐associated protein 1 (ABCC1/MRP1) (Goler‐Baron & Assaraf, 2011); P‐gp transfers a multi‐drug resistance phenotype after EV uptake by recipient cancer cells (Bebawy et al., 2009; Jaiswal et al., 2012).