RIGI and COVID-19: Higher levels of several of these proteins were inversely correlated with viral load, including the cytosolic RNA sensor RIG-I (gene symbol DDX58), chemokines (CCL20 and CCL25), and other proteins (Keratin 19 [KRT19], amphiregulin [AREG]) previously shown to be upregulated in COVID-19 patients (Talla et al., 2021).