This result is consistent with the transcriptome study of Zhang et al.36, 37Subsequently, we confirmed that synaptic development‐related genes SYN1 (Synapsin 1, a neuronal phosphoprotein involving in regulating axonogenesis and synaptogenesis38) and SYNPO (synaptopodin, a marker and essential component of the dendritic spines39) were significantly upregulated in autism, and significantly improved after AVP treatment. The gene discussed is SYN1; the disease is autism.