FCGR2B and systemic lupus erythematosus: In SLE mice with deficiencies in the inhibitory receptor FcγRIIb that lead to the production of antinuclear antibodies and glomerulonephritis, andrographolide inhibited SLE susceptibility in mice by inhibiting NF-κB activity, preventing the progression of antinuclear antibodies and renal injury (Kalergis et al., 2009).