NR1H4 and metabolic dysfunction-associated steatohepatitis: Besides, BV possessed antioxidant, anti-inflammatory, and anti-hyperlipidemic effects against rats nonalcoholic steatohepatitis induced by fructose, which may be due to the enhanced expression of nuclear receptors, liver X receptor α (LXRα) and farnesoid X receptor (FXR), the reduced liver sterol regulatory element-binding protein 1/2 (SREBP1/2) levels, and the improved intestine tight junction protein expression (Abd El-Haleim, 2020).