Besides, in an allograft model, the effect of docetaxel in suppressing breast tumor growth was potentiated by the administration of MEL, and the programmed death ligand-1 (PD-L1) protein expression, phosphorylated HER2 and epidermal growth factor receptor (p-EGFR), were significantly reduced (Duffy et al., 2020). Here, EGFR is linked to breast neoplasm.