BV decreased neutrophil and eosinophil counts in nasal lavage fluid, reduced interferon-γ (INF-γ) level, inflammatory cell infiltration and PAS-positive cells, as well as suppressed NF-κB and activator protein-1 (AP-1) expressions in mouse nasal mucosa, which indicated that BV may possess potential value in treating allergic chronic rhinosinusitis (Shin S. H. et al., 2018). The gene discussed is NFKB1; the disease is bacterial vaginosis.