In addition, a study in Thai ALL pediatric patients found that the average absolute neutrophil count (ANC) at the 6th month of the maintenance phase was significantly lower in ABCC4 SNP rs3765534 carriers, compared to patients carrying wild-type alleles, and the risk of grade 4 neutropenia was higher in ABCC4 GA carriers than wild-type patients, but was not statistically significant (Khaeso et al., 2022). This evidence concerns the gene ABCC4 and neutropenia.