PIK3CA and rheumatoid arthritis: KEGG pathway analysis of 135 DEGs mainly enriched the NF-κB signaling pathway, collecting ductal acid secretion, steroid hormone biosynthesis, rheumatoid arthritis, PI3K/AKT signaling pathway, etc. The pathview-Bioconductor software (version 3.15) was used to show the potential signaling pathways associated with EA treatment of MI (Figure 6(d)).