The positivity rates for aCL and LA were elevated (34% vs. 11%, P<0.01 and 25% vs. 5%, P<0.01, respectively), while the prevalence of anti-β2-GPI antibody positivity increased in the ICVD-SLE group (32% vs. 16%, P=0.07) when compared to the control. The gene discussed is APOH; the disease is systemic lupus erythematosus.