These cells were mapped to CD4+ T cells, CD8+ T cells, B cells, malignant cells, hepatic progenitor-like cells (HPC-like), endothelial cells that expressed PLVAP genes (PLVAP+ ECs, tumor-specific ECs with fetal-like property), endothelial cells that expressed ACKR1 genes (ACKR1+ ECs), cancer-associated fibroblasts (CAFs), tumor-associated macrophages (TAMs), and TAMs that expressed FOLR2 (FOLR2+ TAMs, fetal-like TAMs with immunosuppressive property) according to cell-type-specific marker genes (Figures 4A, , B). The gene discussed is ACKR1; the disease is cancer.