As the AAB targets F2R/PAR-1, CXCR3, and STAB1 are involved in inflammatory processes (89, 90) this finding points to a distinct inflammatory mechanism in cognitive impairment in PCS/ME/CFS in contrast to vasoconstriction in the previous cohort of non-COVID ME/CFS. Here, F2R is linked to myalgic encephalomeyelitis/chronic fatigue syndrome.