In our study, we find that the RR pattern can be accompanied by a variety of autoantibodies, such as anti-RNP/Sm, anti-SSA, anti-AMA-M2, anti-GP210, anti-SP100, anti-SLA, etc. There have been similar reports that the RR pattern could be accompanied by antibodies related to autoimmune hepatitis (19, 45). Here, TRIM21 is linked to autoimmune hepatitis.