In addition to the above diseases, the alterations of IgA1 glycosylation are often accompanied by the development of Crohn’s disease and other autoimmune diseases such as systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), Sjogren’s syndrome, celiac disease (Hansen et al., 2021). The gene discussed is IGHA1; the disease is rheumatoid arthritis.