NPPB and chronic thromboembolic pulmonary hypertension: After the intervention, patients with CTEPH had a significant improvement in cardiac function, illustrated by the improvements in 6-min working distance (6MWD), N-terminal pro-B-type natriuretic peptide (NT-proBNP), world health organization functional class (WHO-FC), and smaller right ventricle (Supplementary Figures 1A–C, 2A–H and Supplementary Table 1).