GSK3B and diabetes mellitus: Western blot demonstrated that compared with the control group, the protein expression levels of Wnt2, β-catenin, WISP1, c-Myc, and p-GSK-3β in the myocardial tissues of the DM group were significantly upregulated (P < 0.001), and downregulated by FXST treatment (P < 0.05 or 0.001, Figures 5(a)–5(g)).