The expression levels of collagen I, collagen III, and TGF-β1 was significantly elevated in the myocardium of the DM group compared with the control group (P < 0.05 or 0.01 or 0.001), nevertheless, FXST downregulated the expression of collagen I, collagen III, and TGF-β1 compared to the DM group (P < 0.05 or 0.01 or 0.001, Figures 4(c)–4(k)). This evidence concerns the gene TGFB1 and diabetes mellitus.