APOB and familial hypercholesterolemia: LDL-C: low-density lipoprotein cholesterol; Apo B: apolipoprotein B-100; Lp(a): total cholesterol lipoprotein(a); HDL-C: high-density lipoprotein cholesterol; ApoA1: apolipoprotein A1; CV: cardiovascular; HeFH: heterozygous familial hypercholesterolemia; HoFH: homozygous familial hypercholesterolemia; MI: myocardial infarction; CRP: C-reactive protein