When there was analysis regarding factors associated with AKI in patients with COVID-19 then it was found that factors like old age, male gender, history of diabetes, hypertension, cardiovascular disease, mechanical ventilation, use of vasoactive medication, and use of angiotensin-converting enzyme-1 (ACE-1) or angiotensin receptor blocker (ARB) were associated with AKI significantly (Table 5). This evidence concerns the gene ACE and acute kidney injury.