JAG1 and Duchenne muscular dystrophy: Not only has greater proliferative capacity been observed with overexpression of Jag1, but this intervention can even ameliorate the DMD phenotype in GRMD, marking it as a potential therapeutic target and indicating that Jag1 may act as a genetic modifier of DMD (Vieira et al., 2015; Gioftsidi et al., 2022).