Compared with adjacent normal tissues, the relative expression levels of EZH2, NSD2, KMT5C, and UHRF1 were higher in PCa tissues (P < 0.05), but no significant differences were found in the expression levels of ORC1 and DNMT3A (P > 0.05) (Figure 4B). Here, UHRF1 is linked to posterior cortical atrophy.