TP53 and Fanconi anemia: KEGG enrichment analysis showed that bub1 was mainly involved in base excision repair, cell cycle, cell senescence, DNA replication, Fanconi anemia pathway, herpes simplex virus 1 infection, homologous recombination, mismatch repair, nucleotide excision repair, one carbon pool by folate, oocyte meiosis, p53 signaling pathway, pyrimidine metabolism, RNA transport and spliceosome processes (Figure 4C; Supplementary Table 2).