The duration of diabetes, hypertension percentage, SBP, antihypertensive drug treatment, ARB/ACEI, other antihypertensive drugs, insulin usage, fasting plasma C-peptide (FC-P), TC, TG, Cr, BUN, 24-h urine protein quantitative (24-h Upro), UACR levels, and diabetic retinopathy rate were significantly higher, while eGFR was obviously lower in the macroalbuminuria group compared with the normoalbuminuria group (Table 2). The gene discussed is INS; the disease is diabetic retinopathy.